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Raman Spectroscopic Analysis of Breast Cancer Tissues: Identifying Differences Between Normal, Invasive Ductal Carcinoma and Ductal Carcinoma in Situ of the Breast Tissue by Shazza Rehman; Zanyar Movasaghi; Art T. Tucker; Simon P. Joel; Jawwad A. Darr; Alexander V. Ruban; Ihtesham U. Rehman is a Chemistry article available to read on EtoBox.
What is Raman Spectroscopic Analysis of Breast Cancer Tissues: Identifying Differences Between Normal, Invasive Ductal Carcinoma and Ductal Carcinoma in Situ of the Breast Tissue about?
## Abstract A relatively non‐destructive method employing Raman spectroscopy for the analysis of histopathological specimens is described. Raman spectroscopy has allowed qualitative analysis of the same specimen used for histopathological evaluation. Breast cancer tissues have been analysed to demonstrate the feasibility of the chemical changes taking place in the biological tissue, which can be identified precisely, and the results are reproducible. Raman analysis of tissue sections provides distinct spectra that can be used to distinguish between the nuclear grades of ductal carcinoma __in situ__ (DCIS) and invasive ductal carcinoma (IDC) of the breast. Sixty cases of breast carcinoma including DCIS and IDC and seven cases of normal breast tissues were studied employing the Raman spectroscopic technique. This study reports for the first time spectral differences between DCIS grades. It is concluded that Raman spectroscopy can objectively distinguish between DCIS and IDC grades and is non‐destructive and reproducible. It should become possible in future to use Raman spectroscopy as an informative and quantitative method suitable for classification of grades and diagnosis of breast
Who reads Raman Spectroscopic Analysis of Breast Cancer Tissues: Identifying Differences Between Normal, Invasive Ductal Carcinoma and Ductal Carcinoma in Situ of the Breast Tissue?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Shazza Rehman; Zanyar Movasaghi; Art T. Tucker; Simon P. Joel; Jawwad A. Darr; Alexander V. Ruban; Ihtesham U. Rehman
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0377-0486)
- Published
- 2007
- Language
- EN
- Field
- Chemistry (Physical Sciences)