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Iodine status in pregnant women in northern Spain. Effect of iodised salt and iodine supplements on thyroid function by Silvia González-Martínez; Eduardo Martínez-Morillo; Noelia Avello-Llano; Ana Isabel Escudero-Gomis; Elías Delgado-Álvarez; Edelmiro Luis Menéndez-Torre is a Medicine article available to read on EtoBox.
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Introduction: Iodine deficiency is linked to thyroid dysfunction, particularly in pregnant women. The objective of this study was to ascertain the iodine levels of women in the second trimester of pregnancy, analysing the influence of iodine ingestion on urinary iodine concentration (UIC) and maternal thyroid function. Methods: A prospective observational study of pregnant women from Health Area IV of Asturias (northern Spain) recruited before 13 weeks of gestation between May and June 2017. A questionnaire on iodine intake was completed at the first visit, and urine and serum samples were collected at baseline and again during the second trimester. UIC, thyroid stimulating hormone (TSH) and free thyroxine (FT4) obtained in the second trimester of gestation were analysed and related to iodine intake. Thyroid autoimmunity was also analysed in half of the pregnant women at baseline. Results: A total of 241 pregnant women were studied. Of these, 56.7% used iodised salt, 46.7% consumed ≥2 servings of dairy products daily and 88.1% took iodine supplements. Median UIC was 191 g/l (135.3---294 g/l), with 68.1% of the women having UIC ≥150 g/l. Only iodised salt consumption provided protec
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- Author
- Silvia González-Martínez; Eduardo Martínez-Morillo; Noelia Avello-Llano; Ana Isabel Escudero-Gomis; Elías Delgado-Álvarez; Edelmiro Luis Menéndez-Torre
- Publisher
- Elsevier BV
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)