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Level of urinary catecholamine in children with Sleep Disordered Breathing: A systematic review and meta-analysis by Esther T.W. Cheng; Raymond N.C. Chan; Kate C.C. Chan; Chun T. Au; Albert M. Li is a Medicine article available to read on EtoBox.

What is Level of urinary catecholamine in children with Sleep Disordered Breathing: A systematic review and meta-analysis about?

Objective: To compare the levels of different urinary catecholamines amongst paediatric patients with and without sleep-disordered breathing (SDB). Methods: Literature searches were conducted on PubMed and EMBASE until 25/06/2022. Inclusion criteria were original human studies, English language, paediatric subjects diagnosed with SDB/ obstructive sleep apnoea (OSA). The quality of studies was assessed by the Newcastle-Ottawa Quality Assessment (NOSGEN). The registered number of this study on the International Prospective Register of Systematic Reviews (PROSPERO) is CRD42022332939. The main outcome measured was standardised mean difference (SMD) of urinary catecholamine between subjects with and without SDB, between those with and without OSA, and also between subjects with mild OSA and those with moderate/ severe OSA. Sensitivity analyses were performed to avoid bias. Results: 9 studies (8 cross-sectional and 1 cohort study) with a total of 838 subjects, were included in the quantitative analysis. Urine level of noradrenaline was higher in patients with SDB, which included primary snoring (PS), when compared to controls: SMD 1⁄4 0.86 (95%CI1⁄40.32e1.41; I 2 1⁄485%, P1⁄40.002). The

Who reads Level of urinary catecholamine in children with Sleep Disordered Breathing: A systematic review and meta-analysis?

Author

Esther T.W. Cheng; Raymond N.C. Chan; Kate C.C. Chan; Chun T. Au; Albert M. Li

Publisher

Elsevier BV

Published

2022

Language

EN

Field

Medicine (Health Sciences)