Can I read Study on Prevention of Postoperative Abdominal Adhesions with PLGA Nanofiber Membrane on EtoBox?

Study on Prevention of Postoperative Abdominal Adhesions with PLGA Nanofiber Membrane by Sun MengQing; Tan RuiZhe; Li Peng; Zou Peng is a Physics and Astronomy article available to read on EtoBox.

What is Study on Prevention of Postoperative Abdominal Adhesions with PLGA Nanofiber Membrane about?

## Abstract Objective: To evaluate the effectiveness of poly (lactic-co-glycolic acid) (PLGA) nanofiber membrane on prevention of postoperative abdominal adhesion. Methods: PLGA nanofiber membrane was prepared by high-voltage electrospinning technique. The effectiveness of the membrane in prevention of postoperative abdominal adhesions was characterized with rat abdominal adhesion models. Results: PLGA nanofiber membrane was prepared successfully by electrospinning technique. Scanning electron microscopy (SEM) observation showed that the average diameter of PLGA fibers was approximately 800 nm, and the membrane had microporous structures. Mechanical tests showed that the tensile strength of PLGA nanofiber membrane was 6.36 ± 0.39 MPa, which was significantly higher than the tensile strength of DIKANG absorbable medical film. The results of in vivo experiments showed that PLGA nanofiber membrane and DIKANG absorbable medical film could both reduce the degree of abdominal adhesions. The histological results showed that there was only a small extent of inflammatory cell infiltration in the PLGA group and the control group. The proliferation of connective tissue was reduced, and so was

Who reads Study on Prevention of Postoperative Abdominal Adhesions with PLGA Nanofiber Membrane?

Author

Sun MengQing; Tan RuiZhe; Li Peng; Zou Peng

Publisher

Institute of Physics; IOP Publishing (ISSN 1742-6588)

Published

2020

Language

EN

Field

Physics and Astronomy (Physical Sciences)