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Genetic networks is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Genetic networks about?

A7-002 DORSOVENTRAL SIGNALING IN DROSOPHILA OOGENESIS, Siegfried Roth, F. Shim Neuman-Silberberg, and T ~d i Schiiphach, In Drosophila, the establishment of the dorsoventral pattern of the egg and embryo involves two signaling events. The first of these takes place in oogenesis and requires the activity of the genes gurken and torpedo/DER (Drosophila EGF receptor hnmolog). gurken was found to encode a TGF-a like molecule and may encode a germline ligand for the top/DER receptor. The gurken RNA and protein are localized to the dorsal anterior comer of the oocyte during midoogenesis. This localization appears to provide the spatially restricted dorsal determinant that induces dorsal development in the follicle cells. The localized gurken signal also serves to orient the future dorsoventral axis of the egg. It delimits the ventral region of the egg and embryo, but it does not appear to directly determine ventral and venmlateral cell fates in the embryo. Rather, top/DER receptor activation represses an active patterning process which involves signaling from the follicle cells to the embryo through the Toll receptor (1.2) on the egg membrane.

Who reads Genetic networks?

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0730-2312)

Published

1995

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)