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Cell-cell adhesion is mediated by transmembrane proteins called cell adhesion molecules (CAMs). The main CAMs are cadherins, selectins, integrins, and the immunoglobulin superfamily. Cadherins form adherens junctions and mediate calcium-dependent homophilic binding. Selectins mediate leukocyte binding to endothelial cells. Integrins provide heterophilic binding between cells and the extracellular matrix. Cell junctions such as tight junctions, adherens junctions, and desmosomes anchor cells together and con
- Author
- Govinda Biswas
- Language
- EN