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Can I read Ultrastructure of Anaplastic (Spindle and Giant Cell) Carcinoma of the Thyroid on EtoBox?
Ultrastructure of Anaplastic (Spindle and Giant Cell) Carcinoma of the Thyroid by Wellington Jao; Victor E. Gould is a Medicine article available to read on EtoBox.
What is Ultrastructure of Anaplastic (Spindle and Giant Cell) Carcinoma of the Thyroid about?
Three anaplastic (spindle and giant cell) carcinomas of the thyroid were studied by light and electron microscopy; two of the tumors also included foci of recognizable follicular carcinoma. The follicular carcinoma cells displayed prominent mitochondria and rough endoplasmic reticulum, and showed evidence of secretory activity. Desmosomes and complex cellular interdigitations were evident. Basal laminae were present, with conspicuous reduplication in the well-differentiated foci. However, some epithelial clusters were surrounded by basal lamina, showing focal discontinuities through which epithelial cells protruded into the stroma. The pleomorphic spindle and giant cells showed cytoplasmic and nuclear characteristics similar to the better differentiated carcinomatous follicular elements, but showed rare desmosomes and no basal laminae. The basic ultrastructural similarity between follicular and anaplastic tumor cells confirms their common epithelial origin. However, while partially retaining their secretory capability, the anaplastic cells progressively lose their capacity to synthetize basal lamina and develop complex cellular attachments. Cancer 351280-1292, 1975. ## NAPLASTIC (S
Who reads Ultrastructure of Anaplastic (Spindle and Giant Cell) Carcinoma of the Thyroid?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Wellington Jao; Victor E. Gould
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0008-543X)
- Published
- 1975
- Language
- EN
- Field
- Medicine (Health Sciences)