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Can I read Hepatoprotective Evaluation of Scoparia dulcis L. on EtoBox?
Hepatoprotective Evaluation of Scoparia dulcis L. by Atish Kumar Sahoo and V. Madhavan is a Medicine article available to read on EtoBox.
What is Hepatoprotective Evaluation of Scoparia dulcis L. about?
Scoparia dulcis L. (Family: Scrophulariaceae) is an herb native to America and in tropics and widely present in Karnataka, India. This plant has been traditionally used to cure many liver aliments. Phytochemical screening has revealed that the plant contains diterpenoids, flavonoids, tannins, alkaloids, triterpenes, hexacosonol, ?-sitosterol, ketone, dulcitone and amellin. Liver cirrhosis represents the common pathological outcome for the majority of chronic liver insults (e.g. alcohol, autoimmune, or viral injury, even oxidative stress). The therapeutic potential of antioxidants with respect to liver toxicity has been realized marginally so far. In the present study the in vitro antioxidant activity and antihepatotoxic activity of hydroalcoholic extract of S. dulcis (HASD) was investigated against CCl4 induced liver damage in rats. The extracts showed in vitro free radical scavenging activity against DPPH free radicals. The in vivo hepatoprotective activity study for HASD extracts at an oral dose of 500 mg/kg and 800 mg/kg, exhibited a significant (P<0.01) protective effect against CCl4 induced changes in serum glutamate oxaloacetate transaminase (SGOT), glutamate pyruvate transam
Who reads Hepatoprotective Evaluation of Scoparia dulcis L.?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Atish Kumar Sahoo and V. Madhavan
- Publisher
- Walter de Gruyter GmbH
- Published
- 2009
- Field
- Medicine (Health Sciences)