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Asthma and Sleep Outcomes in Pediatric Urban Children with & without Atopic Dermatitis by Aquino, Marcella; Kopel, Sheryl; Dunsiger, Shira; Mitchell, Daphne Koinis is a Medicine article available to read on EtoBox.

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RATIONALE: Severe asthma (SA) significantly reduces patients' healthrelated quality of life (HRQoL) and productivity. However, there are no contemporary estimates of HRQoL and productivity from a national, realworld sample of U.S. adults with SA. METHODS: CHRONICLE (NCT03373045) is an ongoing observational study of SA patients treated by U.S. allergists/immunologists or pulmonologists. Eligible patients are adults receiving biologic therapy, those uncontrolled on high-dosage inhaled corticosteroids with additional controllers (HD ICS+) and/or those receiving maintenance systemic corticosteroids (mSCS). At enrollment, patients complete the St. George's Respiratory Questionnaire (SGRQ; referencing prior 3 months, range 0-100, 1005maximum impairment) and Work Productivity and Activity Impairment-Asthma survey (WPAI; referencing prior 7 days, percentage impairment). Responses were summarized by treatment category for patients enrolled February 2018 to February 2019. RESULTS: Of 796 patients enrolled across 89 sites, 481 (60%) completed both surveys. Patient demographics and other characteristics were generally similar for those completing/not completing surveys. For biologic (N5370), H

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Author

Aquino, Marcella; Kopel, Sheryl; Dunsiger, Shira; Mitchell, Daphne Koinis

Publisher

Elsevier Science; Elsevier ; Mosby Inc.; Elsevier BV; SAGE Publications (ISSN 1097-6825)

Published

2020

Language

EN

Field

Medicine (Health Sciences)