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The study investigates the in vitro dissolution and in vivo bioavailability of bromhexine hydrochloride and cefaclor from mono- and bi-component capsule formulations. Results indicate no significant differences in dissolution rates between the base and its salt in mono-component preparations, while bi-component preparations showed a slower solution rate for the base. In vivo, peak plasma levels of both compounds were similar across formulations, suggesting that the combination does not adversely affect abso
- Author
- iris
- Language
- EN