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This study compares the pharmacokinetic properties of α-mangostin and γ-mangostin in rats when administered as pure compounds versus as part of a mangosteen fruit extract. The results indicate that while both compounds undergo significant first-pass metabolism, the administration of the extract leads to slower conjugation and increased exposure to free compounds. The findings suggest that mangosteen fruit extracts may be more beneficial than pure xanthones for health benefits associated with these compounds
- Author
- hanapui
- Language
- EN