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This document describes a study that investigated how Polycomb repressive complex 2 (PRC2) is recruited to transposable elements (TEs) in Paramecium. The study identified proteins that physically interact with the Paramecium enhancer-of-zeste Ezl1 enzyme, which catalyzes H3K9me3 and H3K27me3 deposition at TEs. It was found that PRC2 interacts with the RNA interference (RNAi) effector Ptiwi09 and this interaction is important for TE repression. A RING finger protein was also found to mediate the interaction

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UwU

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EN