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Can I read Universal leukoreduction decreases the incidence of febrile nonhemolytic transfusion reactions to RBCs on EtoBox?
Universal leukoreduction decreases the incidence of febrile nonhemolytic transfusion reactions to RBCs by Karen E. King; R. Sue Shirey; Sandra K. Thoman; Debra Bensen-Kennedy; Warren S. Tanz; Paul M. Ness is a Medicine article available to read on EtoBox.
What is Universal leukoreduction decreases the incidence of febrile nonhemolytic transfusion reactions to RBCs about?
**BACKGROUND:** Febrile nonhemolytic transfusion reactions (FNHTR) is a relatively common complication associated with allogeneic transfusion. Because WBCs have been implicated in the mechanism of FNHTRs, it has been proposed that the transfusion of leukoreduced RBCs should be associated with a decreased incidence of FNHTRs. These reactions are generally not life threatening, but they are expensive in their management, evaluation, and associated blood‐product wastage. Over the past several years, the proportion of leukoreduced RBCs has increased at Johns Hopkins Hospital in an effort to move toward complete leuko‐reduction. A retrospective analysis is reported here of FNHTRs in RBC recipients as the inventory increased in percentage of leukoreduced RBC units. **STUDY DESIGN AND METHODS:** Between July 1994 and December 2001, all transfusion reactions (TRs) associated with the transfusion of allogeneic RBCs were retrospectively analyzed. Both computerized data and individual TR reports were reviewed. Patients who had both allergic and febrile features were included as part of both categories. TRs were reported as a percentage of total units transfused. Two time periods were selected
Who reads Universal leukoreduction decreases the incidence of febrile nonhemolytic transfusion reactions to RBCs?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Karen E. King; R. Sue Shirey; Sandra K. Thoman; Debra Bensen-Kennedy; Warren S. Tanz; Paul M. Ness
- Publisher
- Elsevier Science; John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Elsevier; Elsevier BV; Wiley (ISSN 0372-1248)
- Published
- 2004
- Language
- EN
- Field
- Medicine (Health Sciences)