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Routine coagulation testing in Vacutainer^®^ Citrate Plus tubes filled at minimum or optimal volume by Fiamma Balboni; Stefania Barbui; Marco Gallo; Margherita Berardi; Marco Vezzosi; Giuseppe Lippi is a Medicine article available to read on EtoBox.

What is Routine coagulation testing in Vacutainer^®^ Citrate Plus tubes filled at minimum or optimal volume about?

## Abstract ## Background Filling of citrate tubes with appropriate amount of blood is essential for obtaining reliable results of coagulation testing. This study aimed to verify whether results of routine coagulation tests are comparable when the new Becton Dickinson Vacutainer^®^ Citrate Plus tubes are filled at minimum or optimal volume. ## Methods The study population consisted of 133 patients (40 on oral anticoagulant therapy), who had blood collected for routine coagulation testing. Two sequential Vacutainer^®^ Citrate Plus tubes of the same type and lot were drawn. The first tube was collected after a butterfly needle was inserted into the vein, so that the air in the tubing was aspirated into the tube before blood (minimum fill volume), whilst the second was drawn at optimal fill volume. Experiments were repeated using 2.7-mL (n = 86) and 1.8-mL (n = 47) tubes. ## Results Prothrombin time (PT) and fibrinogen values were slightly but significantly decreased in tubes with minimum than in those with optimal fill volume. The activated partial thromboplastin time (APTT) was slightly prolonged in tubes with minimum than in those with optimal fill volume, but the difference was no

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Author

Fiamma Balboni; Stefania Barbui; Marco Gallo; Margherita Berardi; Marco Vezzosi; Giuseppe Lippi

Publisher

Walter de Gruyter GmbH (ISSN 2194-8011)

Published

2019

Language

EN

Field

Medicine (Health Sciences)