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The document reviews soluble guanylyl cyclase (sGC) activators as promising therapeutic options for heart failure and pulmonary hypertension, highlighting their role in enhancing nitric oxide signaling and increasing cyclic GMP levels. Recent clinical trials have led to the approval of drugs like riociguat and vericiguat for treating chronic thromboembolic pulmonary hypertension and heart failure, respectively. Ongoing research is exploring additional sGC activators and their potential applications in vario
- Author
- sarra.bensouiki88
- Language
- EN