About this Medicine article

An epidemiological study of familial neurocysticercosis in an endemic Mexican community by A. Fleury; J. Morales; R.J. Bobes; M. Dumas; O. Yánez; J. Piña; R. Carrillo-Mezo; J.J. Martínez; G. Fragoso; A. Dessein; C. Larralde; E. Sciutto is a Medicine article available to read on EtoBox.

Neurocysticercosis (NC) caused by Taenia solium is a frequent parasitic disease of the central nervous system. It is highly endemic in many developing countries, where many people are exposed but few become infected. Here, the relevance of age, gender, and genetic and exposure factors on NC susceptibility was studied in 649 inhabitants of a rural community of Mexico. Endemicity was confirmed by the high prevalence of pig cysticercosis (32.8%) and human seroprevalence (43.8%). Human NC cases were diagnosed by computerised tomography scans. A questionnaire to evaluate risk factors was applied and familial relationships between participants were registered. An overall NC frequency of 9.1% (59/649) was found. NC frequency increased with age but did not associate with gender. Most NC cases were asymptomatic. None of the evaluated risk factors were associated with NC. No familial aggregation was detected when studying all cases, although a significant relationship between mother and child in cases with multiple parasites was found. These findings point to the fact that human NC in high exposure conditions is not simply related to exposure factors and they do not support the participation

Author

A. Fleury; J. Morales; R.J. Bobes; M. Dumas; O. Yánez; J. Piña; R. Carrillo-Mezo; J.J. Martínez; G. Fragoso; A. Dessein; C. Larralde; E. Sciutto

Publisher

Elsevier Science; Oxford University Press; Oxford University Press (OUP); ScienceOpen (ISSN 0035-9203)

Published

2006

Language

EN

Field

Medicine (Health Sciences)