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Adv Healthcare Materials - 2024 - Caro - Metabolically Driven Active Targeting of Magnetic Nanoparticles Functionalized by Sofía Martín López is a document available to read on EtoBox.

This research article presents a novel strategy for targeting glioblastoma using iron oxide nanoparticles (IONPs) functionalized with glucuronic acid, which enhances their delivery through glucose transporters overexpressed in glioblastoma cells. The study demonstrates that this metabolically-driven active targeting, combined with mild hypoglycemia, significantly improves the efficacy of magnetic hyperthermia therapy, resulting in notable tumor growth delay in preclinical models. These findings suggest a pr

Author

Sofía Martín López

Language

EN