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What is PRosettaC: Modeling PROTAC Complexes about?

The article presents PRosettaC, a novel protocol for modeling PROTAC-mediated ternary complexes, which are crucial for the effective degradation of target proteins. This protocol combines global and local docking techniques to accurately predict the structures of these complexes, facilitating the rational design of new PROTACs. PRosettaC is made accessible through a web server, allowing researchers to utilize it for designing PROTACs targeting various proteins.

Author

syedanargis214

Language

EN