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Can I read Glycemic control in the diabetic pregnancy: Is tighter always better? on EtoBox?
Glycemic control in the diabetic pregnancy: Is tighter always better? by Barak M. Rosenn; Menachem Miodovnik is a Medicine article available to read on EtoBox.
What is Glycemic control in the diabetic pregnancy: Is tighter always better? about?
Glucose is the principal nutrient that the mother supplies to the fetus through the placenta by way of concentration-dependent mechanisms. In the presence of maternal hypoglycemia, with limited glucose supply, fetal hypoglycemia and hypoinsulinism ensue. This may be viewed as an adaptive mechanism to increase the chances of fetal survival in the face of limited maternal supply, albeit of a growth-restricted fetus. Fetal nutrient deprivation and the resulting hypoinsulinism may have both short- and long-term consequences. Intrauterine growth failure is associated with higher rates of gestational age-specific neonatal mortality and with long-term cognitive deficits. Furthermore, epidemiologic data suggest that diabetes, coronary artery disease, and hypertension are more common among adults who were small for gestational age at birth. Thus, pancreatic failure in adulthood may be either a response to excessive exposure to glucose as a result of maternal hyperglycemia, or as a result of hypoglycemia where nutrient deprivation leads to fetal growth restriction and reduced islet cell proliferation. Because low mean concentrations of maternal glucose in gestational diabetes are associated
Who reads Glycemic control in the diabetic pregnancy: Is tighter always better??
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Barak M. Rosenn; Menachem Miodovnik
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); Parthenon Publishing Group; Wiley (ISSN 1057-0802)
- Published
- 2000
- Language
- EN
- Field
- Medicine (Health Sciences)