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Can I read Analyzing Mitogen‐Activated Protein Kinase (MAPK) Activities in T Cells on EtoBox?
Analyzing Mitogen‐Activated Protein Kinase (MAPK) Activities in T Cells by Alan J. Whitmarsh; Roger J. Davis is a Immunology and Microbiology article available to read on EtoBox.
What is Analyzing Mitogen‐Activated Protein Kinase (MAPK) Activities in T Cells about?
## Abstract The recognition of peptide antigens by T cells through their antigen receptors (T cell receptors, or TCR), together with the ligation of additional surface molecules called costimulatory receptors, rapidly induces interactive signaling pathways that lead to transcriptional initiation at genes such as that of the autocrine growth factor interleukin 2 (IL‐2). Activation of the ERK and JNK subfamilies of MAPK mediates some of these signals. This unit presents procedures for a solid‐phase kinase assay and immune‐complex kinase assay to measure JNK and ERK activities, respectively, in T cells that have been appropriately stimulated. Also described is a procedure for preparing GSThyphen;cJun/GSH‐Sepharose beads needed in the solid‐phase JNK protein kinase activity assay.
Who reads Analyzing Mitogen‐Activated Protein Kinase (MAPK) Activities in T Cells?
It is typically read by researchers, students, and practitioners in Immunology and Microbiology.
- Author
- Alan J. Whitmarsh; Roger J. Davis
- Publisher
- Wiley
- Published
- 2003
- Language
- EN
- Field
- Immunology and Microbiology (Life Sciences)