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British Empire, October, 1944), working in the Department of Obstetrics and Gvnrecologv and Pathology of the Univel'sity of Liverpool, have described a rare condition of intraepidermal cancer of the vulva. It is known by two names-Bowen's disease and Paget's disease; but the authors prefer to use the title of Bowen's disease. Clinically the condition shows as a dull, raw, red area with a clearly defined serpiginous outline. The area is on the same level as the surrounding skin, or at the most is only slightly raised, but there is a sharp line of demarcation between healthy and diseased tissues. The surface is moist, but may become encrusted in part, the appearance being very similar to that of Paget's disease of the nipple. It does not show any of the usual characteristics of malignant disease. There is no friability or fixation, and metastases in lymphatic glands or elsewhere are rare. It may be confused with eczema or with tuberculosis or other ulcers. It is sometimes mistaken for kraurosis or leucoplakia, which may occur in association with Bowen's disease. The disease runs a slow course, often lasting many years. It may at any time change into epithelioma. The symptoms produced

Who reads GYNÆCOLOGY?

Publisher

AMPCo

Published

1945

Field

Social Sciences