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Can I read Comment on “Enterocyte–innate lymphoid cell crosstalk drives early IFNg-mediated control of Cryptosporidium” on EtoBox?
Comment on “Enterocyte–innate lymphoid cell crosstalk drives early IFNg-mediated control of Cryptosporidium” by William A. Petri; Alexandra N. Donlan is a Immunology and Microbiology article available to read on EtoBox.
What is Comment on “Enterocyte–innate lymphoid cell crosstalk drives early IFNg-mediated control of Cryptosporidium” about?
The parasite Cryptosporidia infects and completes its entire life cycle within the intestinal epithelium. It has been long appreciated that interferon gamma is critical for protection, but the source of this cytokine, the mechanism of induction and the cell site of action have been unknown. Here Gullicksrud et al. demonstrate in a mouse model that interferon gamma regulation and protection center on the infected epithelial cell. The work is of importance for the fundamental advances it provides on mucosal defense from intracellular parasitism, as well as providing a foundation for the advancement of vaccination against this cause of diarrhea, malnutrition and death of infants in low and middle income countries.
Who reads Comment on “Enterocyte–innate lymphoid cell crosstalk drives early IFNg-mediated control of Cryptosporidium”?
It is typically read by researchers, students, and practitioners in Immunology and Microbiology.
- Author
- William A. Petri; Alexandra N. Donlan
- Publisher
- Elsevier BV
- Published
- 2022
- Language
- EN
- Field
- Immunology and Microbiology (Life Sciences)