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Usefulness of Drain Amylase, Serum C-Reactive Protein Levels and Body Temperature to Predict Postoperative Pancreatic Fistula After Pancreaticoduodenectomy by Masahide Hiyoshi; Kazuo Chijiiwa; Yoshiro Fujii; Naoya Imamura; Motoaki Nagano; Jiro Ohuchida is a Medicine article available to read on EtoBox.

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## Background: Postoperative pancreatic fistula (popf) after pancreaticoduodenectomy (pd) is a worrisome and life-threatening complication. recently, early drain removal has been recommended as a means of preventing popf. the present study sought to determine how to distinguish clinical popf from non-clinical popf in the early postoperative period after pd to aid in early drain removal. ## Methods: From march 2002 through december 2010, 176 patients underwent pd and were enrolled in this study to examine factors predictive of clinical popf after pd. popf was defined and classified according to the international study group of pancreatic surgery guideline, and grade b/c popf was defined as clinical popf. ## Results: Grade a popf occurred in 39 (22.2 %) patients, grade b in 19 (10.8 %) patients, and grade c in 11 (6.3 %) patients. clinical popf (grade b/c) occurred in 17.1 % of patients. multivariate analysis revealed male gender and body mass index (bmi) ≥22.5 kg/m(2) to be the independent preoperative risk factors predictive of popf. receiver operating characteristic curves showed that the combination of drain amylase ≥750 iu/l, c-reactive protein (crp) ≥20 mg/dl, and body temperat

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Author

Masahide Hiyoshi; Kazuo Chijiiwa; Yoshiro Fujii; Naoya Imamura; Motoaki Nagano; Jiro Ohuchida

Publisher

Springer Science and Business Media LLC

Published

2013

Language

EN

Field

Medicine (Health Sciences)