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Can I read Determination of disopyramide and its mono-N-dealkylated metabolite in blood serum and urine on EtoBox?
Determination of disopyramide and its mono-N-dealkylated metabolite in blood serum and urine by T.C. Hutsell; S.J. Stachelski is a Chemistry article available to read on EtoBox.
What is Determination of disopyramide and its mono-N-dealkylated metabolite in blood serum and urine about?
A rapid, precise and accurate assay for disopyramide and mono-N-dealkylated disopyramide concentrations in blood serum and urine is described. The method involves extraction of the drugs from a basic aqueous medium into chloroform, derivatization of the metabolite, purification of the extract and gas chromatographic analysis using an OV-17 liquid phase and flame ionization detection. Unique characteristics of the procedure, direct derivatization in the organic phase and the use of Florisil to separate the drugs from interfering materials, should be applicable to the analysis of other basic drugs in biological specimens.
Who reads Determination of disopyramide and its mono-N-dealkylated metabolite in blood serum and urine?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- T.C. Hutsell; S.J. Stachelski
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 1873-3778)
- Published
- 1975
- Language
- EN
- Field
- Chemistry (Physical Sciences)