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Can I read Application of Adaptive Laboratory Evolution in Lipid and Terpenoid Production in Yeast and Microalgae on EtoBox?
Application of Adaptive Laboratory Evolution in Lipid and Terpenoid Production in Yeast and Microalgae by Yu-Lei Jia; Jin Li; Fang-Tong Nong; Chun-Xiao Yan; Wang Ma; Xiao-Feng Zhu; Li-Hui Zhang; Xiao-Man Sun is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Application of Adaptive Laboratory Evolution in Lipid and Terpenoid Production in Yeast and Microalgae about?
Due to the complexity of metabolic and regulatory networks in microorganisms, it is difficult to obtain robust phenotypes through artificial rational design and genetic perturbation. Adaptive laboratory evolution (ALE) engineering plays an important role in the construction of stable microbial cell factories by simulating the natural evolution process and rapidly obtaining strains with stable traits through screening. This review summarizes the application of ALE technology in microbial breeding, describes the commonly used methods for ALE, and highlights the important applications of ALE technology in the production of lipids and terpenoids in yeast and microalgae. Overall, ALE technology provides a powerful tool for the construction of microbial cell factories, and it has been widely used in improving the level of target product synthesis, expanding the range of substrate utilization, and enhancing the tolerance of chassis cells. In addition, in order to improve the production of target compounds, ALE also employs environmental or nutritional stress strategies corresponding to the characteristics of different terpenoids, lipids, and strains.
Who reads Application of Adaptive Laboratory Evolution in Lipid and Terpenoid Production in Yeast and Microalgae?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Yu-Lei Jia; Jin Li; Fang-Tong Nong; Chun-Xiao Yan; Wang Ma; Xiao-Feng Zhu; Li-Hui Zhang; Xiao-Man Sun
- Publisher
- American Chemical Society (ACS)
- Published
- 2023
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)