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Presepsin levels in neonatal cord blood are not influenced by maternal SARS-CoV-2 infection by Francesca Priolo; Simona Fattore; Marta Tedesco; Domenico Umberto De Rose; Roberto Chioma; Alessandro Perri; Simonetta Costa; Serena Antonia Rubortone; Maria Letizia Patti; Annamaria Sbordone; Luca Maggio; Giovanni Vento is a Medicine article available to read on EtoBox.

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## Abstract ## Objectives Coronavirus disease (COVID-19) can present with various symptoms and can involve multiple organs. Women infected during pregnancy have a higher incidence of obstetrical complications and infants born to “positive” mothers may get the infection with different manifestations. Presepsin seems to be a promising sepsis biomarker in adults and neonates. The aim of this study was to assess if presepsin levels in neonatal cord blood could be influenced by maternal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. ## Methods A total of 119 neonates born from women with a confirmed diagnosis of SARS-CoV-2 infection were enrolled and presepsin levels of cord blood samples were collected. All neonates were tested for SARS-CoV-2 infection at birth and after 48–72 h. ## Results The median presepsin value in umbilical cord blood samples collected after birth was 455 pg/mL. Presepsin levels were not influenced by maternal symptoms of COVID-19, weight for gestational age, or delivery mode, and did not significantly differ between infants with and without adverse neonatal outcomes. Infants hospitalized for more than 5 days had a significantly higher pr

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Author

Francesca Priolo; Simona Fattore; Marta Tedesco; Domenico Umberto De Rose; Roberto Chioma; Alessandro Perri; Simonetta Costa; Serena Antonia Rubortone; Maria Letizia Patti; Annamaria Sbordone; Luca Maggio; Giovanni Vento

Publisher

Walter de Gruyter GmbH

Published

2022

Language

EN

Field

Medicine (Health Sciences)