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1) AQP4 knockout mice and wild-type mice were given brain abscesses via injection of live Staphylococcus aureus encased in agarose beads into the striatum. 2) At 3 days, AQP4 knockout mice had significantly higher intracranial pressure and brain water content compared to wild-type mice, indicating more severe brain swelling. 3) The findings suggest AQP4 plays a protective role in reducing brain swelling associated with bacterial brain abscesses, likely by facilitating clearance of excess water from the br

Author

Iqbal Abdillah

Language

EN