About this document
T Cell Activation and Signaling Mechanisms by aagrawal is a document available to read on EtoBox.
The document discusses T cell activation which requires three main signals: 1) TCR binding antigen on MHC, 2) co-stimulation such as CD28 binding CD80/86, and 3) cytokine signaling such as IL-2. The signals result in T cell proliferation and differentiation into effector and memory cells. The document also mentions inhibitory signals such as CTLA4 and PD-1 that regulate T cell activation.
- Author
- aagrawal
- Language
- EN