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Skin cancer incidence in transgender individuals receiving gender‐affirming hormone treatment: a nationwide cohort study in the Netherlands by Amirun Rahmat; Iris De Nie; Chantal M. Wiepjes; Martin Den Heijer; Thomas Rustemeyer; Christel J. M. De Blok; Koen M. A. Dreijerink is a Medicine article available to read on EtoBox.

What is Skin cancer incidence in transgender individuals receiving gender‐affirming hormone treatment: a nationwide cohort study in the Netherlands about?

Background Development of skin cancer, in particular melanoma, has been linked to sex hormones. We aimed to determine the incidence of skin cancer in transgender individuals receiving gender-affirming hormone treatment (GAHT). Methods In this nationwide retrospective cohort study, clinical information of participants who visited our clinic between (the years) 1972 and 2018 and received GAHT was integrated with national pathology and cancer statistics data in order to assess skin cancer incidence. Standardized incidence ratios (SIRs) were calculated. Results The cohort consisted of 2,436 trans women and 1,444 trans men. The median age at the start of GAHT was 31 years (IQR 24-42) in trans women and 24 years (IQR 20-32) in trans men. The median follow-up time for trans women was 8 years (IQR 3-18) with a total follow-up time of 29,152 years and 4 years (IQR 2-12) with a total follow-up time of 12,469 years for trans men. Eight trans women were diagnosed with melanoma (SIR 1.80 [95% CI 0.83-3.41] vs. all men; SIR 1. 40 [0.65-2.65] vs. all women), and seven developed squamous cell carcinoma (SIR 0.78 [0.34-1.55] vs. all men; SIR 1.15 [0.50-2.27] vs. all women). Two trans men developed

Who reads Skin cancer incidence in transgender individuals receiving gender‐affirming hormone treatment: a nationwide cohort study in the Netherlands?

Author

Amirun Rahmat; Iris De Nie; Chantal M. Wiepjes; Martin Den Heijer; Thomas Rustemeyer; Christel J. M. De Blok; Koen M. A. Dreijerink

Publisher

Wiley

Published

2023

Language

EN

Field

Medicine (Health Sciences)