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Can I read A Free Vein Graft Cap Influences Neuroma Formation After Nerve Transection on EtoBox?
A Free Vein Graft Cap Influences Neuroma Formation After Nerve Transection by Mariarosaria Galeano; Benedetto Manasseri; Giovanni Risitano; Stefano Geuna; Federica Di Scipio; Paola La Rosa; Gabriele Delia; Francesco Stagno D'Alcontres; Michele R. Colonna is a Medicine article available to read on EtoBox.
What is A Free Vein Graft Cap Influences Neuroma Formation After Nerve Transection about?
## Abstract ## Introduction: Neuroma formation is a major problem in nerve surgery and consensus about its prevention has not been reached. It has been suggested that vein covering can reduce neuroma formation in transected nerves. In this article, the Authors propose an easy and novel method of covering by nerve stump capping with a free vein graft. ## Methods: Neuroma‐like lesions were created on the rat thigh sectioning the femoral nerve above its division in 16 animals. The proximal nerve stump was invaginated into the lumen of a 1.5 cm long femoral free vein graft on the right side, and the vein was closed on itself by microsurgical sutures to form a cap for the nerve stump. On the left side acting as the control neuroma, the nerve was cut and left uncovered. Histological and immunohistochemical assessment was used to quantify the degree of neuroma formation. ## Results: Significant differences were found in both neuroma size and axon‐glia organization between the treated and control sides indicating that free vein graft capping reduced neuroma formation in comparison to uncovered nerve stumps. ## Conclusions: Our results confirm that vein‐covering of a transected nerve stump
Who reads A Free Vein Graft Cap Influences Neuroma Formation After Nerve Transection?
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- Author
- Mariarosaria Galeano; Benedetto Manasseri; Giovanni Risitano; Stefano Geuna; Federica Di Scipio; Paola La Rosa; Gabriele Delia; Francesco Stagno D'Alcontres; Michele R. Colonna
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0738-1085)
- Published
- 2009
- Language
- EN
- Field
- Medicine (Health Sciences)