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New Weakly Expressed Cell Cycle-regulated Genes in Yeast by Ulrik de Lichtenberg; Rasmus Wernersson; Thomas Skøt Jensen; Henrik Bjørn Nielsen; Anders Fausbøll; Peer Schmidt; Flemming Bryde Hansen; Steen Knudsen; Søren Brunak is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is New Weakly Expressed Cell Cycle-regulated Genes in Yeast about?
## Abstract We present an approach combining bioinformatics prediction with experimental microarray validation to identify new cell cycle‐regulated genes in __Saccharomyces cerevisiae__. We identify in the order of 100 new cell cycle‐regulated genes and show by independent data that these genes in general tend to be more weakly expressed than the genes identified hitherto. Among the genes not previously suggested to be periodically expressed we find genes linked to DNA repair, cell size monitoring and transcriptional control, as well as a number of genes of unknown function. Several of the gene products are believed to be phosphorylated by Cdc28. For many of these new genes, homologues exist in __Schizosaccharomyces pombe__ and __Homo sapiens__ for which the expression also varies with cell cycle progression. Copyright © 2005 John Wiley & Sons, Ltd.
Who reads New Weakly Expressed Cell Cycle-regulated Genes in Yeast?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Ulrik de Lichtenberg; Rasmus Wernersson; Thomas Skøt Jensen; Henrik Bjørn Nielsen; Anders Fausbøll; Peer Schmidt; Flemming Bryde Hansen; Steen Knudsen; Søren Brunak
- Publisher
- John Wiley and Sons; Wiley (Blackwell Publishing); John Wiley & Sons Inc.; [Chichester]; [New York]: John Wiley & Sons, ©1985-; Wiley; Hindawi Limited (ISSN 0749-503X)
- Published
- 2005
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)