Can I read Studies of a DNA marker (G8) genetically linked to Huntington disease in British families on EtoBox?
Studies of a DNA marker (G8) genetically linked to Huntington disease in British families by Sandra Youngman; M. Sarfarazi; O. W. J. Quarrell; P. M. Conneally; Karen Gibbons; P. S. Harper; D. J. Shaw; R. E. Tanzi; Margaret R. Wallace; J. F. Gusella is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Studies of a DNA marker (G8) genetically linked to Huntington disease in British families about?
Close genetic linkage has been shown between the DNA sequence G8 (locus D4S10) and 16 British families with Huntington disease using the HindIII, EcoR1, Nci1, and Pst1 polymorphisms detected by G8, and by combining all the polymorphisms to give a combined haplotype. Two recombinants have been detected in these families giving a maximum lod score of 17.60 at a theta of 0.02. These results confirm the originally reported linkage between the loci and provide evidence against significant multilocus heterogeneity for Huntington disease.
Who reads Studies of a DNA marker (G8) genetically linked to Huntington disease in British families?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Sandra Youngman; M. Sarfarazi; O. W. J. Quarrell; P. M. Conneally; Karen Gibbons; P. S. Harper; D. J. Shaw; R. E. Tanzi; Margaret R. Wallace; J. F. Gusella
- Publisher
- Springer; Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 0340-6717)
- Published
- 1986
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)