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What is Understanding the Biopharmaceutics Classification System about?

This review article summarizes the Biopharmaceutics Classification System (BCS), which classifies drugs based on their permeability and solubility. The BCS framework allows waiving of in vivo bioequivalence studies in favor of in vitro tests under certain criteria. The article discusses criteria for classifying drugs according to BCS classes and potential extensions of biowaivers based on gastrointestinal physiology. Methods for determining drug solubility and permeability are also outlined. The BCS provide

Author

Aileen Ang

Language

EN