About this Medicine article
National cancer institute sponsored study of classifications of non-hodgkin's lymphomas. Summary and description of a working formulation for clinical usage by The Non-Hodgkin's Lymphoma Pathologic Classification Project is a Medicine article available to read on EtoBox.
An international multi-institutional clinicopathologic study of 1175 cases of non-Hodgkin's lymphoma sponsored hy the National Cancer Institute has been completed. Histologic slides and clinical records were examined from previously untreated patients seen during the period between July 1971 and December 1975 a t four institutions, three in the United States and one in Italy. The reproducibility and clinical relevance of the six major classifications of the non-Hodgkin's lymphomas was tested by six ''expert'' pathologists, each a proponent of a major classification, and six very experienced pathologists not identified with one of the major classifications. Immunologic methods were not employed in the study design. A summary of the methods employed and the conclusions of the study is described. The major conclusion was that all six classifications were valuable and comparable in reproducibility and clinical correlations. The clinical significance of a follicular architecture, independent of cell type was confirmed. A working formulation of non-Hodgkin's lymphomas is described which separates the disease into ten major types utilizing morphologic criteria only. Subtypes are also desc
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- Author
- The Non-Hodgkin's Lymphoma Pathologic Classification Project
- Publisher
- Wiley
- Published
- 1982
- Language
- EN
- Field
- Medicine (Health Sciences)