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Microwave treatment of intracerebral l1210 leukemia: Schedule-dependent partial reversal of the effects of methotrexate by Dr. Barbara K. Chang; Andrew T. Huang; William T. Joines is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

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## Abstract One‐GHz microwave (MW) irradiation at a power density of 5 mW/cm^2^ was combined with methotrexate (MTX) in an attempt to treat more effectively central nervous system (CNS) L1210 leukemia in DBA/2J mice. When mice with CNS leukemia were treated with the combination of MW and MTX, there was no improvement in survival compared with a group of animals treated with MTX alone; however, the group that received MTX before the MW exposure had a significantly reduced survival time compared with the group treated with MTX alone or with the group to which MTX was administered after MW.

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Author

Dr. Barbara K. Chang; Andrew T. Huang; William T. Joines

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0197-8462)

Published

1981

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)