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What is Pharmacogenetics and Drug Response Variability about?

This document discusses pharmacogenetics and pharmacogenomics. It begins by providing examples of interindividual variability in drug response rates for various diseases and drug classes. It then discusses factors contributing to this variability, including genetics. The key concepts of monogenic versus polygenic variations and normal versus polymorphic distributions are introduced. Examples of genetic polymorphisms that can affect drug pharmacokinetics and pharmacodynamics are provided, including variation

Author

Adinda Tobing

Language

EN