About this document
PIIS2372770523000372 by sukiextra is a document available to read on EtoBox.
The document presents a novel method called DIStinct-seq for integration site (IS) analysis in CAR-T cell therapies, which allows for rapid and quantitative detection of IS with less than 500 ng of DNA. This method improves upon existing techniques by reducing the time and DNA requirements for library preparation, enabling better monitoring of clonal dynamics and safety in gene therapies. The findings suggest that DIStinct-seq can enhance the understanding of clonal behavior in CAR-T cells and improve the e
- Author
- sukiextra
- Language
- EN