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academically thorough and convincing, that summarized the "rapid progress" and "soon to be revealed discoveries". We found no major genes even for the strongest candidate such as Tourette's. Instead, we found hundreds of common variants of small effects that constitute the heritability of mental disorders. These are no different from the many genes of small effect size that affect most traits such as height, cholesterol level, activity level, sleep depth and other normal physiological and behavioral functions. In no psychiatric illness do we have a clear cut-off for diagnosis based on a gene [2]. 2. Lithium: Lithium was my first love and I was a member of one of the first groups in the USA to give this compound with an IND (investigational new drug) license at Duke Hospital in 1970 when I was a still a medical student. Sam Gershon called lithium the "first salvo in the psychopharmacological revolution". It seemed that a compound so simple with no metabolism, that exits the body the same ways it enters and that is mined in the earth rather than synthesized, must be capable of giving us a peek into the window of the mind. Lithium seemed so similar to sodium and potassium, the importa
- Author
- Robert Haim Belmaker; Pesach Lichtenberg
- Publisher
- Springer International Publishing AG
- Published
- 2023
- Language
- EN
- ISBN
- 9783031403705
- Subjects
- Medical, Science, Psychology
- Rating
- 2.08 / 5 (25 ratings)
- Updated
- 2026-03-14
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