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Cytochrome P450 in Antineoplastic Drug Metabolism by Geraldine Borda is a document available to read on EtoBox.
What is Cytochrome P450 in Antineoplastic Drug Metabolism about?
This document discusses the role of cytochrome P450 enzymes in the metabolism of antineoplastic drugs. Specifically, it mentions: 1) Cytochrome P450 enzymes, especially the CYP3A subfamily, are the main enzymes responsible for metabolizing most antineoplastic drugs. 2) The products of reactions catalyzed by these enzymes can be inactive molecules or have antitumor properties, depending on if the substrate is an active drug or an inactive prodrug. 3) Genetic polymorphisms and drug interactions that indu
- Author
- Geraldine Borda
- Language
- EN