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Transcriptomic and Proteomic Evidence For Noncanonical Hydrogen Sulfide Metabolism and Immune Dysregulation in Down Syndrome by giang.openai is a document available to read on EtoBox.
This study investigates the relationship between hydrogen sulfide metabolism and immune dysregulation in individuals with Down Syndrome (DS) through transcriptomic and proteomic analyses. It highlights elevated superoxide dismutase 1 (SOD1) expression linked to inflammatory conditions and suggests a noncanonical pathway for hydrogen sulfide overproduction distinct from cystathionine-β-synthase (CBS). The findings contribute to understanding the oxidative stress and immune dysfunction associated with DS, ext
- Author
- giang.openai
- Language
- EN