About this Engineering article
Artificial Tear Adsorption on Soft Contact Lenses: Methods to Test Surfactant Efficacy by V. Rebeix; F. Sommer; B. Marchin; D. Baude; Tran Minh Duc is a Engineering article available to read on EtoBox.
Spoilage is a primary factor in the biocompatibility of soft contact lenses (SCL) within the lacrimal #uid. Tears are a complex mixture of proteins, lipids, natural surfactants and salts. The spoilation process is due to a contribution of all these components and of the nature of SCL materials themselves. The aim of this study was to set up methods to observe and quantify lacrimal deposits and to select e$cient surfactants for preventing protein deposits. The present study was performed on PMMA-NVP SCL. The behaviour of SCL in presence of tears was studied by means of an in vitro arti"cial tear model consisting of the main tears components and quanti"ed by a colorimetric technique (BCA) performed directly on the lenses. The nature of the deposit was observed directly by atomic force microscopy (AFM) in a liquid medium showing the same adsorption trend noticed in the quantitative results and identifying speci"c adsorption sites. The assessment of surfactant adsorption was performed using Maron's method, as a mean to evaluate the a$nity of surfactant to the surface, while the action of selected surfactants on pre-treated SCL was assessed using the BCA method. Promising results were o
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- Author
- V. Rebeix; F. Sommer; B. Marchin; D. Baude; Tran Minh Duc
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0142-9612)
- Published
- 2000
- Language
- EN
- Field
- Engineering (Physical Sciences)