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CDX-622: Dual Inhibition of SCF & TSLP by chukaisioji is a document available to read on EtoBox.
What is CDX-622: Dual Inhibition of SCF & TSLP about?
The study presents CDX-622, a bispecific antibody designed to inhibit mast cell activation and Type 2 inflammatory responses by targeting stem cell factor (SCF) and thymic stromal lymphopoietin (TSLP). In vitro and in vivo experiments demonstrated that CDX-622 effectively neutralizes SCF and TSLP, leading to significant reductions in proinflammatory markers without toxicity in non-human primates. This dual inhibition approach may enhance clinical outcomes for patients with inflammatory disorders driven by t
- Author
- chukaisioji
- Language
- EN