About this Chemistry article
Two-Photon CQDs-Based Dual-Mode Nanoprobe for Fluorescence Imaging and Magnetic Resonance Imaging of Intracellular Wide pH by Hongmei Zhong; Yong-Xiang Wu; Shengrong Yu; Xiao Wang; Kangdi He; Dian Li; Yuting Cao; Ning Gan is a Chemistry article available to read on EtoBox.
Biological fluorescence imaging technologies have attracted a lot of attention and have been widely used in biomedical fields. Compared with other technologies, fluorescence imaging has a lower cost, higher sensitivity, and easier operation. However, due to the disadvantages of one-photon (OP) fluorescence imaging, such as low spatial and poor temporal resolution and poor tissue permeability depth, the application of OP fluorescence imaging has some limitations. Though two-photon (TP) fluorescence imaging can well overcome these shortcomings of OP, the single-mode imaging remains deficient. Therefore, dual-mode imaging combined with TP imaging and magnetic resonance imaging (MRI) can make up for the deficiency well, which make dual-mode imaging for the early diagnosis of diseases more accurate. Hence, a dual-mode nanoprobe TP-CQDs@MnO 2 was designed for probing the fluorescence/MR dual-mode imaging strategy of intracellular H + by using TP-CQDs (two photon-carbon quantum dots) and MnO 2 nanosheets. The MnO 2 nanosheets treated as fluorescence quenching agents of TP-CQDs exhibited a supersensitive response to H + , which made the fluorescence signals turn "off" to "on" for TP fluore
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Hongmei Zhong; Yong-Xiang Wu; Shengrong Yu; Xiao Wang; Kangdi He; Dian Li; Yuting Cao; Ning Gan
- Publisher
- American Chemical Society (ACS)
- Published
- 2021
- Language
- EN
- Field
- Chemistry (Physical Sciences)