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Adjuvant Chemotherapy of Breast Cancer by Richard G. Cooper; James F. Holland; Oliver Glidewell is a Medicine article available to read on EtoBox.

What is Adjuvant Chemotherapy of Breast Cancer about?

One hundred women with primary breast cancer with 4 or more metastatic axillary nodes were treated for 9 months postoperatively with vincristine, prednisone, cyclophosphamide, methotrexate, and fluorouracil (VPCMF). Sixty-five women have been observed for a minimum of 5 years or until failure and the rest for 3 years or more. For 73 women who received adjuvant chemotherapy only, observed for 5% years median, disease-free status by life table analysis is 68% at 8 years. No significant difference was found between response of pre-and postmenopausal women in disease-free interval or survival. Mortality compared to expectation was sharply reduced; only 9 of 73 have died. These findings demonstrate the long term effectiveness of relatively short-term surgical adjuvant combination chemotherapy in pre-and postmenopausal patients with breast cancer at righ risk. Cancer 44:793-798, 1979. URGERY ALONE IS NOT an adequate life-S saving procedure in women with breast cancer who demonstrate axillary metastases. Although 76% of women without axillary metastases are still disease-free at ten years, this figure drops to 35% for those with 1,2, or 3 nodes involved with metastases, and to 14% for tho

Who reads Adjuvant Chemotherapy of Breast Cancer?

Author

Richard G. Cooper; James F. Holland; Oliver Glidewell

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0008-543X)

Published

1979

Language

EN

Field

Medicine (Health Sciences)