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A New Prognostic Scoring System Using Factors Available Preoperatively to Predict Survival After Operative Resection of Perihilar Cholangiocarcinoma by Hiroki Saito; Takehiro Noji; Keisuke Okamura; Takahiro Tsuchikawa; Toshiaki Shichinohe; Satoshi Hirano is a Medicine article available to read on EtoBox.
What is A New Prognostic Scoring System Using Factors Available Preoperatively to Predict Survival After Operative Resection of Perihilar Cholangiocarcinoma about?
## Background: Perihilar cholangiocarcinoma has one of the poorest prognoses of all cancers. however, mortality and morbidity rates after surgical resection are 0-15% and 14-66%, respectively. additionally, the 5-year overall survival rates are reported at 22-40%. these findings indicate that only selected patients achieve satisfactory beneficial effects from operative treatment. this retrospective study sought to investigate preoperatively available prognostic factors and establish a new preoperative staging system to predict survival after major hepatectomy of perihilar cholangiocarcinoma. ## Patients and methods: We evaluated 121 consecutive patients who underwent operative exploration for perihilar cholangiocarcinoma. ## Results: Univariate and multivariate analysis using the identified preoperative factors revealed that 4 factors (platelet-lymphocyte ratio [plr] > 150, serum c-reactive protein [crp] levels > 0.5 mg/dl, albumin levels 7.0 ng/ml) were independent prognostic factors of postoperative survival. these 4 preoperative factors were allocated 1 point each. the total score was defined as the preoperative prognostic score (pps). patients with a pps of 0, 1, 2, or 3/4 ha
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- Author
- Hiroki Saito; Takehiro Noji; Keisuke Okamura; Takahiro Tsuchikawa; Toshiaki Shichinohe; Satoshi Hirano
- Published
- 2015
- Language
- EN
- Field
- Medicine (Health Sciences)