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Vascularization Enhances Islet Organoid Maturity by Yousef Elyoussef is a document available to read on EtoBox.
The study investigates whether vascularization can enhance the functional maturity of stem-cell-derived islet organoids, aiming to generate functional insulin-secreting β-cells. The authors developed vascularized organoids and utilized various technical approaches, including microfluidics and single-cell RNA sequencing, to assess β-cell function. They concluded that vascularization significantly improves the maturation and functionality of these organoids, with implications for diabetes research and potenti
- Author
- Yousef Elyoussef
- Language
- EN