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CRISPR Therapeutics: Challenges & Future by Hazela Afif is a document available to read on EtoBox.

What is CRISPR Therapeutics: Challenges & Future about?

The document discusses the transformative impact of CRISPR-Cas nucleases on therapeutic development, highlighting their ability to identify drug mechanisms and facilitate cell replacement therapies. It addresses the limitations of Cas9 in vivo, including delivery challenges and off-target effects, while presenting advancements such as biomolecule-Cas9 conjugates and base editors. The paper emphasizes the role of CRISPR screens in drug discovery and validation, as well as the ongoing challenges and future di

Author

Hazela Afif

Language

EN