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- Sulfonylureas work by stimulating insulin secretion from the pancreatic beta cells by closing ATP-sensitive potassium channels. They become less effective if beta cell function declines. Common side effects include hypoglycemia and weight gain. - Biguanides like metformin increase glucose uptake in muscle and inhibit glucose production and absorption to lower blood glucose levels. They may cause gastrointestinal side effects. - Thiazolidinediones improve insulin sensitivity in muscle, adipose tissue and
- Author
- Poppy
- Language
- EN