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AD is a chronic relapsing disease characterized by pruritis and chronic inflammatory skin changes, (1) which affects approximately 10–30% of children and as much as 10% of adults worldwide.(2) This condition has a great significant impact on morbidity and presents an outstanding social economic burden.(3) AD is a multifactorial disease that develop by interaction between these factors in a positive feedback cycle. Treatment of AD interrupts the causal pathway. Management with conventional

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IJAR JOURNAL

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EN