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Association of Thin Basement Membrane Nephropathy with Hypercalciuria, Hyperuricosuria and Nephrolithiasis by Manuel Praga; Miguel Angel Martínez; Amado Andrés; Raquel Alegre; Julia Vara; Enrique Morales; Juan Carlos Herrero; Olga Novo; José Luis Rodicio is a Medicine article available to read on EtoBox.
What is Association of Thin Basement Membrane Nephropathy with Hypercalciuria, Hyperuricosuria and Nephrolithiasis about?
## Background: Familial persistent microhematuria with normal renal function is the most common presentation of thin basement membrane nephropathy (tbmn). gross hematuria episodes and loin pain attacks are other manifestations of the disease. on the other hand, it has been shown that hypercalciuria (hc) and hyperuricosuria (hu) can produce both gross or microscopic non-glomerular hematuria, in addition to their role in renal stone formation. ## Methods: We studied the prevalence of hc, hu and nephrolithiasis in a group of 27 biopsy-proven tbmn as well as in 19 non-biopsied first-degree relatives with persistent microhematuria and 25 first-degree relatives without microhematuria. a group of 27 patients with iga nephropathy (igan) and persistent microhematuria, and another group of 20 healthy subjects without known renal diseases were selected as control groups. ## Results: Ten (37%) patients with tbmn and 8 (42%) relatives with microhematuria showed hc and/or hu at presentation; relatives without microhematuria, igan patients and normal controls showed a significantly lower prevalence of hc and hu. the prevalence of previous nephrolithiasis among tbmn patients (25%) was significantl
Who reads Association of Thin Basement Membrane Nephropathy with Hypercalciuria, Hyperuricosuria and Nephrolithiasis?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Manuel Praga; Miguel Angel Martínez; Amado Andrés; Raquel Alegre; Julia Vara; Enrique Morales; Juan Carlos Herrero; Olga Novo; José Luis Rodicio
- Publisher
- Elsevier BV
- Published
- 1998
- Language
- EN
- Field
- Medicine (Health Sciences)